INVESTIGATING INFLAMMATION IN THE BRAIN

Neuroinflammation refers to the inflammatory response within the brain. Our main research focus is to investigate the role of neuroinflammation in the diseased and healthy brain.

Microglia are the major immune cells in the brain. Therefore, the majority of our projects aim to explore the function of these cells and to determine how they contribute to health and disease. In addition, we investigate how lifestyle-related factors, such as physical inactivity and stress, affect neuroinflammation and contribute to brain pathology. 

Our research ranges from utilizing experimental models, such as in vitro microglia and in vivo mouse models, to conducting epidemiological investigations on the Swedish population. We combine traditional immunohistochemistry, ELISA, western blot, and animal behavioral tests with novel methods such as transcriptomics, proteomics, bioinformatics, and infrared spectroscopy.